Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] | E-AB-F1192A

Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] | E-AB-F1192A | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3

Swissprot Code: Q8TDQ0

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Research Areas: Cancer, Immunology

Backgroun: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300

Purification Method: N/A

Dilution: N/A

Clone: RMT3-23

Conjugation: Unconjugated

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A