Purified Anti-Mouse CD80 Monoclonal Antibody | DL20093F

Purified Anti-Mouse CD80 Monoclonal Antibody | DL20093F | Gentaur UK, US & Europe Distribution

Host: Armenian Hamster

Synonyms: T-lymphocyte activation antigen CD80, Cd80, Activation B7-1 antigen, B7

Reactivity: Mouse

Application: FCM, IHC, IP

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: 16-10A1

Isotype: Armenian Hamster IgG