PUS10 Polyclonal Antibody | E-AB-13544

PUS10 Polyclonal Antibody | E-AB-13544 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CCDC139, Coiled coil domain containing 139, Coiled coil domain containing protein 139, Coiled-coil domain-containing protein 139, DOBI, FLJ32312, MGC126729, Pseudouridine synthase 10, Pseudouridylate synthase 10, Psi55 synthase, pus10, PUS10, Putative tRNA pseudouridine synthase Pus10, tRNA pseudouridine 55 synthase, tRNA pseudouridylate synthase, tRNA uridine isomerase, tRNA-uridine isomerase

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Background: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PUS10

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 60 kDa

Molecular Weight(Observed): N/A