PVRL4 Antibody (Center) [APR04261G]

PVRL4 Antibody (Center) [APR04261G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PVRL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-266 amino acids from the Central region of human PVRL4.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction. Note=Colocalizes with AFDN at cadherin- based adherens junctions (PubMed:11544254)

Molecular Weight: 55454

Clone: Polyclonal

Gene Name: NECTIN4 (HGNC:19688)

Gene ID: 81607

Function: Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.

Summary: Tissue Location: Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Nectin-4, Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4, Processed poliovirus receptor-related protein 4, PVRL4, LNIR, PRR4