Description
Pyridoclax(MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM). Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells.
Pyridoclax(MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM). Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells.
Alternate Name/Synonyms: (E)-3'-methyl-3''-styryl-3,2':5',2'':5'',3'''-quaterpyridine; MR29072
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1651890-44-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₉H₂₂N₄
Molecular Weight: 426.51
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent Mcl-1 inhibitor
MDL Number: N/A
PubChem CID: 92042827
SMILES: CC1=C(N=CC(=C1)C2=C(C=C(C=N2)C3=CN=CC=C3)C=CC4=CC=CC=C4)C5=CN=CC=C5
InChi: InChI=1S/C29H22N4/c1-21-15-27(20-32-28(21)25-10-6-14-31-18-25)29-23(12-11-22-7-3-2-4-8-22)16-26(19-33-29)24-9-5-13-30-17-24/h2-20H,1H3/b12-11+
InChi Key: WGGSYXQFYRWBEC-VAWYXSNFSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |