Description
Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.
Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.
Alternate Name/Synonyms: N1-hydroxy-N8-3-pyridinyl-octanediamide
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 382180-17-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₉N₃O₃
Molecular Weight: 265.31
Cell-Permeable?: Yes
Purity: ≥95%
Solubilities: DMSO (~ 10 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent HDAC1 inhibitor
MDL Number: MFCD13194970
PubChem CID: 4996
SMILES: C1=CC(=CN=C1)NC(=O)CCCCCCC(=O)NO
InChi: InChI=1S/C13H19N3O3/c17-12(15-11-6-5-9-14-10-11)7-3-1-2-4-8-13(18)16-19/h5-6,9-10,19H,1-4,7-8H2,(H,15,17)(H,16,18)
InChi Key: PTJGLFIIZFVFJV-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |