QNZ46 | B2007

QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC₅₀ values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively)

QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC₅₀ values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively)

B2007 | QNZ46 DataSheet

Alternate Name/Synonyms: (E)-4-(6-methoxy-2-(3-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)-benzoic acid

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1237744-13-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₁₇N₃O₆

Molecular Weight: 443.42

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A NR2C/NR2D-selective NMDA receptor non-competitive antagonist

MDL Number: N/A

PubChem CID: 46861929

SMILES: COC1=CC2=C(C=C1)N=C(N(C2=O)C3=CC=C(C=C3)C(=O)O)C=CC4=CC(=CC=C4)[N+](=O)[O-]

InChi: InChI=1S/C24H17N3O6/c1-33-19-10-11-21-20(14-19)23(28)26(17-8-6-16(7-9-17)24(29)30)22(25-21)12-5-15-3-2-4-18(13-15)27(31)32/h2-14H,1H3,(H,29,30)/b12-5+

InChi Key: GNLVJIICVWDSNI-LFYBBSHMSA-N