65

QuantiChrom™ Glyoxalase I Assay Kit

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SKU:
65-DGLO-100-GEN
Availability:
In Stock
$2,756.60

Description

QuantiChrom™ Glyoxalase I Assay Kit

 

Application: For quantitative determination of glyoxalase activity. Note: use a UV plate (e.g. 96-well UV plate, cat# P96UV).

Key Features:

  • Fast and sensitive. Detection Limit 4 U/L GLO-1 Activity.
  • Convenient and high-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day.

Method: OD240nm

Samples: Enzyme preparations or biological samples

Species: All

Size: 100 tests

Detection Limit: 4 U/L

Shelf Life: 12 months

More Details:

GLYOXALASE I (GLO-1), a lactoylglutathione lyase also known as methylglyoxalase, aldoketomutase, ketone-aldehyde mutase, and (R)-S-lactoylglutathione methylglyoxal-lyase, is an enzyme that catalyzes the isomerization of hemithioacetal adducts which are formed in spontaneous reactions between glutathionyl groups and aldehydes. The primary physiological function of glyoxalase I is the detoxification of methylglyoxal, a reactive 2-oxoaldehyde that is cytostatic at low concentrations and cytotoxic at millimolar concentrations.

Glyoxalase I is a target for the development of pharmaceuticals against bacteria, protozoans and human cancer. Simple, direct and automation-ready procedures for measuring GLO-1 activity in biological samples are highly desirable in research and drug discovery.

Gentaur Genprice Glyoxalase I assay kit provides a sensitive and convenient method for GLO-1 activity determination. The method involves monitoring the increase in the product of the GLO-1 reaction, S-lactoylglutathione, by measuring the change in absorbance at 240 nm.

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Additional Information

Application:
Quantitative determination of glyoxalase activity by colorimetry (240nm).
Procedure:
30 min
Size:
100 Tests
Shelf life:
12 months
Shipping:
RT
Storage:
RT, -20°C.
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