Quetiapine hemifumarate | B3284

Quetiapine fumarate Displays antagonist activity at serotonin (5-HT2) and dopamine (D2) receptors (IC50 values are 148 and 329 nM respectively). Lacks affinity at either D1 or muscarinic receptors. Acts as an atypical antipsychotic agent.

Quetiapine fumarate Displays antagonist activity at serotonin (5-HT2) and dopamine (D2) receptors (IC50 values are 148 and 329 nM respectively). Lacks affinity at either D1 or muscarinic receptors. Acts as an atypical antipsychotic agent.

B3284 | Quetiapine hemifumarate DataSheet

Alternate Name/Synonyms: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate

Appearance: White solid

Formulation:

CAS Number: 111974-72-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₅N₃O₂S.0.5C₄H₄O₄

Molecular Weight: 441.54

Cell-Permeable?: True

Purity: ≥98%

Solubilities: >20 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A 5-HT2 antagonist

MDL Number: MFCD03423782

PubChem CID: 5281025

SMILES: C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=CC(=O)O)C(=O)O

InChi: InChI=1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChi Key: ZTHJULTYCAQOIJ-WXXKFALUSA-N