Quinol 2 | 2437

A potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel. Shows potent antitumor activity in HCT 116 and HT 29 human colon as well as MCF 7 and MDA 468 human breast cancer cell lines. Also displays in vivo antitumor activity against human RXF 944XL renal xenografts in nude NMRI mice. Inhibits thioredoxin reductase with potencies correlated with their antiproliferative and cytotoxic efficacies.

Quinol 2 is a potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel.

2437 | Quinol 2 DataSheet

Alternate Name/Synonyms: 4-Benothiazol-2-yl-4-hydroxy-cyclohexa-2,5-dienone

Appearance: Crystalline solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₉FNO₂S

Molecular Weight: 243.29

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent and selective antitumor agent

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(C=C1)C=CC1(O)C2=NC3=C(S2)C=CC=C3

InChi: InChI=1S/C13H9NO2S/c15-9-5-7-13(16,8-6-9)12-14-10-3-1-2-4-11(10)17-12/h1-8,16H

InChi Key: SDYBYKXWYDVVKP-UHFFFAOYSA-N