(-)-Quinpirole hydrochloride | B2994

Quinpirole is a dopamine D2 receptor agonist with Ki values of 4.8 nM, 24 nM, 30nM and 1900 nM at D2, D3, D4 and D1 receptors respectively. Quinpirole inhibits single pulse dopamine overflow in a concentration-dependent manner with an IC₅₀ of 32.5 nM.

Quinpirole is a dopamine D2 receptor agonist with Ki values of 4.8 nM, 24 nM, 30nM and 1900 nM at D2, D3, D4 and D1 receptors respectively. Quinpirole inhibits single pulse dopamine overflow in a concentration-dependent manner with an IC₅₀ of 32.5 nM.

B2994 | (-)-Quinpirole hydrochloride DataSheet

Alternate Name/Synonyms: (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrazolo[3,4-g]quinoline,hydrochloride; (4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline hydrochloride; LY 171555; Dopamine D₂ Receptor Agonist

Appearance: Off-white powder

Formulation:

CAS Number: 85798-08-9

Structure Available?: True

Peptide sequence:

Salt Form: True

Molecular Formula: C₁₃H₂₂ClN₃

Molecular Weight: 255.79

Cell-Permeable?: True

Purity: >98%

Solubilities: ~6 mg/ml in DMSO, ~25 mg/ml in Water

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A dopamine D2 receptor agonist

MDL Number: MFCD00069336

PubChem CID: 55397

SMILES: CCCN1CCCC2C1CC3=C(C2)NN=C3.Cl

InChi: InChI=1S/C13H21N3.ClH/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12;/h9-10,13H,2-8H2,1H3,(H,14,15);1H/t10-,13-;/m1./s1

InChi Key: HJHVRVJTYPKTHX-HTMVYDOJSA-N