(R)-(+)-Etomoxir | B1104

R-(+)-Etomoxir is a carnitine palmitoyltransferase I (CPT1) inhibitor which is required for the oxidation of long chain acyl CoA esters. It inhibits β-oxidation in mitochondria and shown to inhibit biosynthesis of cardiolipin from exogenous fatty acid in H9c2 cells. Potential antidiabetic drug.

R-(+)-Etomoxir is a carnitine palmitoyltransferase I (CPT1) inhibitor which is required for the oxidation of long chain acyl CoA esters. It inhibits β-oxidation in mitochondria and shown to inhibit biosynthesis of cardiolipin from exogenous fatty acid in H9c2 cells. Potential antidiabetic drug.

B1104 | (R)-(+)-Etomoxir DataSheet

Alternate Name/Synonyms: (R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid, ethyl ester

Appearance: Off-white Solid

Formulation: N/A

CAS Number: 124083-20-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Yes

Molecular Formula: C₁₇H₂₃ClO₄

Molecular Weight: 326.81

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>8 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A carnitine palmitoyltransferase I (CPT1) inhibitor

MDL Number: MFCD11227266

PubChem CID: 60765

SMILES: CCOC(=O)C1(CO1)CCCCCCOC2=CC=C(C=C2)Cl

InChi: InChI=1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m0/s1

InChi Key: DZLOHEOHWICNIL-KRWDZBQOSA-N