RAB11FIP1 polyclonal Antibody | BS61249

RAB11FIP1 polyclonal Antibody | BS61249 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein. Rab11-FIP1, by interacting with Rab GTPases, is involved in the endosomal recycling process and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis. Localized to the recycling endosome, the cytoplasmic membrane and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing. As the most highly expressed isoform, isoform two of Rab11-FIP1 is expressed in brain, lung, testis, small intestine, spleen and heart. Isoform two of Rab11-FIP1 also has been found to form a homooligomer and is believed to interact with many Rab GTPases, including Rab 4A, Rab 11A, Rab 11B and Rab 25.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RAB11FIP1 polyclonal Antibody detects endogenous levels of RAB11FIP1 protein.

Molecular Weight: ~ 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Rab11 family-interacting protein 1; Rab11-FIP1; Rab-coupling protein; RAB11FIP1; RCP

Immunogen: A synthetic peptide corresponding to residues in Human RAB11FIP1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: