RAB22A Antibody (C-term) [AMM07440G]

RAB22A Antibody (C-term) [AMM07440G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This RAB22A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-192 amino acids from the C-terminal region of human RAB22A.

Cellular Localisation: Endosome membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Cell membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Early endosome. Late endosome {ECO:0000250|UniProtKB:P51154}. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.

Molecular Weight: 21855

Clone: Polyclonal

Gene Name: RAB22A

Gene ID: 57403

Function: Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905) . Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477) . Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Ras-related protein Rab-22A, Rab-22, RAB22A, RAB22