Description
RAB27B Antibody [AMM07459G] | Gentaur UK, US & Europe Distribution
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H, M
Specificity: This RAB27B antibody is generated from a mouse immunized with a recombinant protein of human RAB27B.
Cellular Localisation: Membrane; Lipid-anchor. Late endosome
Molecular Weight: 24608
Clone: Monoclonal
Gene Name: RAB27B
Gene ID: 5874
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381) . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604) . May be involved in targeting uroplakins to urothelial apical membranes (By similarity) .
Summary: Tissue Location: Expressed primarily in testis.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: N/A
Dilution: WB--1:2000
Synonyms: Ras-related protein Rab-27B, C25KG, RAB27B