RAB27B Antibody [AMM22290G]

RAB27B Antibody [AMM22290G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M

Specificity: This RAB27B antibody is generated from a mouse immunized with a recombinant protein of human RAB27B.

Cellular Localisation: Membrane; Lipid-anchor. Late endosome

Molecular Weight: 24608

Clone: Monoclonal

Gene Name: RAB27B

Gene ID: 5874

Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381) . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604) . May be involved in targeting uroplakins to urothelial apical membranes (By similarity) .

Summary: Tissue Location: Expressed primarily in testis.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Ras-related protein Rab-27B, C25KG, RAB27B