RAB27BAntibody (C-term) [AMM07458G]

RAB27BAntibody (C-term) [AMM07458G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This RAB27B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human RAB27B.

Cellular Localisation: Membrane; Lipid-anchor. Late endosome

Molecular Weight: 24608

Clone: Polyclonal

Gene Name: RAB27B

Gene ID: 5874

Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381) . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604) . May be involved in targeting uroplakins to urothelial apical membranes (By similarity) .

Summary: Tissue Location: Expressed primarily in testis.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Ras-related protein Rab-27B, C25KG, RAB27B