Rabbit Anti-Human Artemin Antibody | 102-P217

Rabbit Anti-Human Artemin Antibody | 102-P217 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Rabbit

Comment: N/A

Label: N/A

Clone / Antibody feature: Rabbit IgG

Subcategory: Polyclonal Antibody

Category: Antibody

Synonyms: ARTN; EVN; NBN; ENOVIN

Isotype: N/A

Application: ELISA, WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: highly pure (>98%) recombinant hArtemin

Description: Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRα (α1-α4) receptors. Artemin prefers the receptor GFRα3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons. The functional human Artemin ligand is a disulfide-linked homodimer, of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration. Recombinant human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized from PBS

Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 9048