Rabbit Anti-Human PAI-1 Antibody | 102-P246

Rabbit Anti-Human PAI-1 Antibody | 102-P246 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Rabbit

Comment: N/A

Label: N/A

Clone / Antibody feature: Rabbit IgG

Subcategory: Polyclonal Antibody

Category: Antibody

Synonyms: PAI-1

Isotype: N/A

Application: ELISA, WB, N

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: Recombinant Human PAI-1

Description: As a member of the Serpin superfamily of serine protease inhibitors, Serpin E1/PAI1 is the principal inhibitor of urokinase-type plasminogen activator (uPA) and tissue type plasminogen activator (tPA). As important regulators of extracellular matrix remodeling, uPA and PAI 1 play a major role in many processes such as angiogenesis, tumor invasion and obesity. For example, uPA and PAI1 are the only tumor prognostic factors validated at the highest level of evidence with regard to their clinical utility in breast cancer. The human PAI1 is initially synthesized as 402 amino acid precursor with a Nterminal signal peptide. PAI 1 may exist in one of two possible conformations, designated as active or latent.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized from PBS

Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 5054