Rabbit Anti-Rat VEGF-D Antibody | 104-PA12S/104-PA12

Rabbit Anti-Rat VEGF-D Antibody | 104-PA12S/104-PA12 | Gentaur UK, US & Europe Distribution

Species: Anti-Rat

Host / biotech: Rabbit

Comment: N/A

Label: N/A

Clone / Antibody feature: Rabbit IgG

Subcategory: Polyclonal Antibody

Category: Antibody

Synonyms: vascular endothelial growth factor D; Figf

Isotype: N/A

Application: WB, E

Detection Range: Western Blot: Use 2-5 µg/ml

Species Reactivity/Cross reactivity: Rat

Antigen: N-terminal peptide

Description: Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), is a vascular endothelial growth factor. This secreted protein is a member of the platelet derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and performs activities in angiogenesis, lymphangiogenesis, and endothelial cell growth. Human VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. It is structurally and functionally similar to VEGF-C, and is secreted as a non-covelent homodimer in a antiparallel fashion. VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. Like VEGFC, it may particularly be involed in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 360457