Rad51 (T309) polyclonal Antibody | BS3729

Rad51 (T309) polyclonal Antibody | BS3729 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Rad51 (T309) polyclonal Antibody detects endogenous levels of Rad51 protein.

Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BRCC5; DNA repair protein RAD51 homolog 1; E coli RecA homolog; HGNC:9817; HRAD51; Homolog of E coli RecA; HsRad51; HsT16930; RAD51 S cerevisiae homolog; RAD51 homolog S. cerevisiae; RAD51A; RECA; Rad 51; RecA homolog E. coli; RecA like protein;

Immunogen: Synthetic peptide, corresponding to amino acids 280-330 of Human Rad51.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Cell Cycle Control G1 S Checkpoint,G Protein-coupled Receptors Signaling to MAPK Erk,Cell Cycle G2 M DNA Damage Signaling Pathway,