RAET1E, human recombinant | 7327

RAET1E belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. RAET1E and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human RAET1E protein, fused to His-tag at N-terminus, was expressed in E.coli.

7327 | RAET1E human recombinant DataSheet

Biomolecule/Target: RAET1E

Synonyms: NKG2D ligand 4, bA350J20.7, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4

Alternates names: NKG2D ligand 4, bA350J20.7, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4

Taglines: A ligand for NKG2D receptor

NCBI Gene ID #: 6288

NCBI Gene Symbol: SAA1

Gene Source: Human

Accession #: P0DJI8

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 microgram of protein

Activity (Specifications/test method): N/A

Biological activity: For most in vitro applications, apo-SAA exerts its biological activity in the concentration range of 10-50 µg/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 24.9 kDa (219 aa, 31-225 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.4 M Urea.

Reconstitution Instructions: Reconstitute in 0.1% acetic acid to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A