RALBP1 polyclonal Antibody | BS91151

RALBP1 polyclonal Antibody | BS91151 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC FC

Application Range: WB:1:1,000-1:5,000 FC:1:50-1:100 IHC:1:50-1:200

Background: Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins) . Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: RALBP1 polyclonal Antibody detects endogenous levels of RALBP1 protein.

Molecular Weight: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DNP-SG ATPase, RALBP1, RLIP1, 76 kDa Ral-interacting protein, 76-kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, Ral-interacting protein 1, 76-KD, RalA-binding protein 1, RalBP1, RBP1, RIP1, RLIP1, RLIP76,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: