Ramipril | B2133

Ramipril is a non-peptide, angiotensin converting enzyme (ACE) inhibitor (IC₅₀ = 5 nM). A prodrug that is hydrolyzed in vivo to the active metabolite ramiprilat. Displays protective effects on endothelium against high-glucose induced dysfunction. Displays antihypertensive effects.

Ramipril is a non-peptide, angiotensin converting enzyme (ACE) inhibitor (IC₅₀ = 5 nM). A prodrug that is hydrolyzed in vivo to the active metabolite ramiprilat. Displays protective effects on endothelium against high-glucose induced dysfunction. Displays antihypertensive effects.

B2133 | Ramipril DataSheet

Alternate Name/Synonyms: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-cyclopenta[b]pyrrole-2-carboxylic acid; Altace; HOE498

Appearance: White solid

Formulation: N/A

CAS Number: 87333-19-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₃₂N2₂O₅

Molecular Weight: 416.51

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent angiotensin converting-Enzyme (ACE) inhibitor

MDL Number: MFCD00865775

PubChem CID: 5362129

SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O

InChi: InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1

InChi Key: HDACQVRGBOVJII-JBDAPHQKSA-N