RAP1A Polyclonal Antibody | E-AB-13927

RAP1A Polyclonal Antibody | E-AB-13927 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C21KG, G-22K, GTP-binding protein smg p21A, KREV1, RAP1A, RAP1A, member of RAS oncogene family, RAP1A, Ras-related protein 1A, Ras-related protein Krev-1, Ras-related protein Rap-1A, SMGP21

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human RAP1A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A