RAP2A Antibody (N-Term) [ApR04914G]

RAP2A Antibody (N-Term) [ApR04914G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This RAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-38 amino acids from human RAP2A.

Cellular Localisation: Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note=May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995) . Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443) .

Molecular Weight: 20615

Clone: Polyclonal

Gene Name: RAP2A

Gene ID: 5911

Function: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Ras-related protein Rap-2a, RbBP-30, RAP2A