RAPGEF1 monoclonal Antibody | MB64829

RAPGEF1 monoclonal Antibody | MB64829 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: IF, IHC, WB

Application Range: WB 1:400~4000, IHC 1:150, IF 1:100

Background: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: Rap guanine nucleotide exchange factor 1

Molecular Weight: 122.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: C3G; GRF2

Immunogen: Full length human recombinant protein of human RAPGEF1 (NP_941372) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A