RASSF6 Antibody | 6543

RASSF6 Antibody | 6543 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Mouse: (93%) , Rat: (93%)

Immunogen: RASSF6 antibody was raised against a 14 amino acid synthetic peptide near the center of human RASSF6.
The immunogen is located within amino acids 230 - 280 of RASSF6.

Research Area: Apoptosis

Tested Application: E, WB

Application: RASSF6 antibody can be used for detection of RASSF6 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: RASSF6 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: RASSF6 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: RASSF6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: RASSF6 Antibody: Ras association domain-containing protein 6

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: RASSF6 Antibody: RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6) , a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ-B pathway and may play a vital role in infection.