Rat Anti-human Indian Hedgehog Antibody | 101-M720

Rat Anti-human Indian Hedgehog Antibody | 101-M720 | Gentaur UK, US & Europe Distribution

Species: Anti-human

Host / biotech: Rat

Comment: N/A

Label: N/A

Clone / Antibody feature: (#9L16)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: N/A

Isotype: IgG2

Application: WB

Detection Range: WB: 1:500-1000

Species Reactivity/Cross reactivity: Human

Antigen: Recombinant Human Indian Hedgehog N-Terminus

Description: Indian Hedgehog (Ihh), Sonic Hedgehog (Shh), and Desert Hedgehog (Dhh) are important signaling molecules during embryonic development and are highly conserved within and across species. Mouse Ihh cDNA encodes a 411 amino acid (aa) polypeptide with a predicted 27 aa signal peptide. Post-translational processing yields a 19 kDa lipid-modified N-terminal domain that is the signaling molecule. At the cell surface, Ihh activity is mediated by binding the 12-pass transmembrane receptor, Patched (Ptc), and signaling through the 7-pass transmembrane G-protein coupled receptor, Smoothened (Smo).

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 3549