Rat Anti-Mouse ALS Antibody | 103-M304

Rat Anti-Mouse ALS Antibody | 103-M304 | Gentaur UK, US & Europe Distribution

Species: Anti-Mouse

Host / biotech: Rat

Comment: N/A

Label: N/A

Clone / Antibody feature: (#4K23)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: Igfals; ALS; Albs; mKIAA4111

Isotype: IgG1

Application: WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Mouse

Antigen: recombinant protein of ALS

Description: ALS (Acid labile subunit) is an 84-86 kDa glycoprotein member of the leucine rich repeat superfamily of molecules. It is secreted by hepatocytes in response to growth hormone stimulation, and forms a 140-150 kDa ternary complex with IGFBP3 (or IGFBP5) and IGFI. This complex increases the half-life of IGFI and retains it in the circulation for use in multiple tissues. Mature mouse ALS is 580 amino acids (aa) in length (aa 24-603). It contains twentyone 20-23 aa LRRs that participate in proteinprotein interactions. There are two potential isoform variants that show N-terminal extensions. One contains a 66 aa substitution for aa 1 -5, while another possesses an 89 aa substitution again for aa 15. Over aa 28-603, mouse ALS shares 79% and 93% aa identity with human and rat ALS, respectively.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 16005