Rat Anti-Mouse CD25 Antibody | 103-M107

Rat Anti-Mouse CD25 Antibody | 103-M107 | Gentaur UK, US & Europe Distribution

Species: Anti-Mouse

Host / biotech: Rat

Comment: N/A

Label: N/A

Clone / Antibody feature: (#7G19)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: CD25; Il2r; Ly-43; interleukin 2 receptor, alpha chain; Il2ra

Isotype: IgG1

Application: IHC, FC

Detection Range: N/A

Species Reactivity/Cross reactivity: Mouse

Antigen: Recombinant Mouse CD25 protein

Description: The biological effects of interleukin 2 (IL-2) are mediated by its binding to a multi-chain cellular receptor complex. The IL-2 receptor (IL-2 R) complex consists of three glycoprotein chains. The alpha chain (IL-2 R alpha /CD25) and beta chain (IL-2 R beta /CD122) act together with the gamma chain (IL-2 R gamma /CD132) to form a high affinity receptor that transduces the signal upon IL-2 binding. Alone, IL-2 R alpha binds IL-2 with low affinity, but is unable to transduce a signal. The alpha/beta combination binds IL-2 with intermediate affinity, but is still unable to transmit a signal inside the cell. The beta/gamma complex has intermediate affinity and is capable of signaling if the concentration of IL-2 is relatively high.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 16184