Description
Rat Anti-Mouse Junctional adhesion molecule B (JAM-B) Antibody | 103-M258 | Gentaur UK, US & Europe Distribution
Species: Anti-Mouse
Host / biotech: Rat
Comment: N/A
Label: N/A
Clone / Antibody feature: (#2K15)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Jam2; JAM-2; JAM-B; Jcam2; VE-JAM; 1110002N23Rik; 2410030G21Rik; 2410167M24Rik
Isotype: IgG2
Application: WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Mouse
Antigen: Mouse recombinant EC domain of JAM-B
Description: Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 67374