Rat IFN-γ protein | PRP1214

Rat IFN-γ protein | PRP1214 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from Rat IFN-γ isoform (P01581) (Glu23-Cys156) was expressed.

Activity: N/A

protein Lenght: The recombinant Rat IFN-γ consists of 134 amino acids and has a predicted molecular mass of 14.8 kDa. The apparent molecular mass of the Rat IFN-γ protein is approximately 14.8 kDa in SDS-PAGE under reducing conditions .

Preparation: E. coli

Purity: ≥ 95% as determined by SDS-PAGE

Formulation: Lyophilized from sterile 20 mM Tris, 150 mM NaCl pH 7.0.

Kit Component: N/A

Features & Benefits : N/A

Molecular Weight: 14.8 kDa

Usage Note: Always centrifuge tubes before opening . It is recommended to centrifuge at 12000 rpm for 1 minute.Then reconstitute the lyophilized Rat IFN-gamma protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Rat IFN-γ proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.126% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: IFN-γ, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN-γ is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN-γ has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN-γ is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-γ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.

Alternative Names: N/A

Search Names: N/A

Tag: IFN-γ