RBBP5 (1C9) monoclonal Antibody | MB0173

RBBP5 (1C9) monoclonal Antibody | MB0173 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:1000 IF: 1:50~200

Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of RBBP5 and does not cross-react with related proteins.

Molecular Weight: Predicted band size:59KDa Observed band size:70KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RBBP 5; RBBP-5; RBBP5; RBBP5_HUMAN; RBQ 3; RBQ3; Retinoblastoma binding protein 5; Retinoblastoma binding protein RBQ3; Retinoblastoma binding protein5; Retinoblastoma-binding protein 5; Retinoblastoma-binding protein RBQ-3; SWD1; SWD1, Set1c WD40 repeat protein, homolog.

Immunogen: Purified recombinant human RBBP5 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Translational Contral Regulation of elF2,