RBBP6 Antibody | 22-593

RBBP6 Antibody | 22-593 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human RBBP6 (NP_116015.2) .

Research Area: Apoptosis, Cancer, Cell Cycle

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: HL-60

Positive Control 2: Jurkat

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 160kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: MY038, P2P-R, PACT, RBQ-1, SNAMA, E3 ubiquitin-protein ligase RBBP6, RB-binding Q-protein 1, RING-type E3 ubiquitin transferase RBBP6, p53-associated cellular protein of testis, proliferation potential-related protein, protein P2P-R, retinoblastoma binding protein 6, retinoblastoma-binding Q protein 1, retinoblastoma-binding protein 6

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.