RBM22 polyclonal Antibody | BS70916

RBM22 polyclonal Antibody | BS70916 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB 1:500 - 1:2000

Background: RBM22, also designated Zinc finger CCCH domain-containing protein 16, is a highly conserved RNA binding protein that is predominantly expressed in spleen and is localized to the nucleus. With a RRM (RNA recognition motif domain) and a C3H1-type zinc finger, RBM22 is primarily involved in pre-mRNA splicing. In the presence of RBM22, cytosolic ALG-2 (Apoptosis Linked Gene 2) translocates to the nucleus, suggesting a functional interaction between the two proteins. Homologs of RBM22 are essential proteins in the regulation of alternative splicing in the cell cycle, zebrafish development and Drosophilia heart development.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RBM22 polyclonal Antibody detects endogenous levels of RBM22 protein.

Molecular Weight: ~ 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Pre-mRNA-splicing factor RBM22; RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16; RBM22; ZC3H16

Immunogen: Recombinant protein of human RBM22.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: