Description
RCHY1 Polyclonal Antibody | E-AB-52167 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Androgen receptor N terminal interacting protein, Androgen receptor N-terminal-interacting protein, ARNIP, CH-rich-interacting match with PLAG1, CHIMP, E3 ubiquitin-protein ligase Pirh2, hARNIP, hPirh2, p53 induced protein with a RING H2 domain, p53-induced RING-H2 protein, PIRH2E, PIRH2F, PRO1996, RCHY1, Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase, RING finger and CHY zinc finger domain-containing protein 1, RING finger protein 199, RNF199, ZCHY, ZFP 363, zinc finger CHY type, Zinc finger protein 363, ZN363, ZNF363
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Concentration: 0.84 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human RCHY1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 30 kDa
Molecular Weight(Observed): Refer to figures