Recombinant Human Eotaxin-2 (CCL24) Protein [E. coli] | 100-013S/100-013

Recombinant Human Eotaxin-2 (CCL24) Protein [E. coli] | 100-013S/100-013 | Gentaur UK, US & Europe Distribution

Species: Human

Host / biotech: E. coli

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Cytokines & Growth Factors

Category: Recombinant Protein

Synonyms: CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24

Isotype: N/A

Application: N/A

Detection Range: Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50-100 ng/ml.

Species Reactivity/Cross reactivity: Mouse, Human, Bacteria

Antigen: N/A

Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemo attracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multi potential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses

Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)

Formulation: lyophilized

Storage Handling Stability: N/A

Reconstituation: N/A

Molecular Weight: 8.8 kDa

Lenght (aa): 78

Protein Sequence: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA

NCBI Gene ID: 6369