Recombinant Human Fibroblast Activation Protein | P1702

Fibroblast activation protein (FAP), also known as seprase, is a homodimeric integral protein gelatinase belonging to the serine protease family. FAP has been implicated in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

P1702 | Recombinant Human Fibroblast Activation Protein DataSheet

Biomolecule/Target :

Synonyms: Fibroblast activation protein, DPPIV Protein, DPPIV, FAPA, Fapalpha Protein, SIMP Protein, Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, Fibroblast activation protein alpha, FAPalpha, Gelatine degradation protease FAP, Integral membrane serine protease, Post-proline cleaving enzyme, Serine integral membrane protease, SIMP, Surface-expressed protease, Seprase

Alternates names:

Taglines: Active Human FAP with C-terminal His-Tag

NCBI Gene ID #: 2191

NCBI Gene Symbol:

Gene Source: Human

Accession #: Q12884

Recombinant: True

Source: Baculovirus

Purity by SDS-PAGE: ≥ 90% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1 EU per 1 ug of protein as determined by LAL method

Activity (Specifications/test method): Specific activity is > 5,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyzes 1.0 pmole of Z-GP-AMC per minute at pH 7.5, at 37 °C.

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 86.1 kDa

Concentration: 0.25 mg/mL

Appearance: Liquid protein

Physical form description: Liquid

Reconstitution Instructions:

Amino acid sequence: The target is expressed with the sequence from amino acid 26 to 760 with a His-Tag at the C-terminus

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans