Description
Recombinant Human GDF-10 Protein [E. coli] | 100-390 | Gentaur UK, US & Europe Distribution
Species: Human
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: GDF10; BMP3B; BMP-3b
Isotype: N/A
Application: N/A
Detection Range: Data not available.
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: GDF-10 is a member of the BMP family and the TGF-beta superfamily. GDF-10 is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and has a role in head formation and possibly multiple roles in skeletal morphogenesis. In humans, GDF-10 mRNA is found in the cochlea and lung of fetuses, and in testis, retina, pineal gland, and other neural tissues of adults. The BMP family members are regulators of cell growth and differentiation in both embryonic and adult tissues. These proteins are characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing 7 conserved cysteine residues. GDF-10 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 111 amino acids (369-478 a.a.) and having a total molecular mass of 12.5 kDa.
Purity Confirmation: > 95% by SDS-PAGE
Endotoxin: N/A
Formulation: liquid
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 12.5 Kd
Lenght (aa): 111
Protein Sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R
NCBI Gene ID: 2662