Recombinant Human pIgR Protein | P1701

The polymeric immunoglobulin receptor is a carrier that transports IgA and IgM across epithelium. The human pIgR has been implicated as a prognostic biomarker for hepatocellular carcinoma progression and metastasis.

P1701 | Recombinant Human pIgR Protein DataSheet

Biomolecule/Target :

Synonyms: FLJ22667 MGC125361; MGC125362 Polymeric immunoglobulin receptor, PIGR, PIgR, Poly-Ig receptor, Hepatocellular carcinoma-associated protein TB6, polymeric immunoglobulin receptor precursor

Alternates names:

Taglines: Binds and transports polymeric IgA and IgM

NCBI Gene ID #: 5284

NCBI Gene Symbol:

Gene Source: Human

Accession #: P01833

Recombinant: False

Source: Baculovirus

Purity by SDS-PAGE: ≥ 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Activity (Specifications/test method):

Biological activity: Measured by its binding ability in a functional ELISA with Human IgM. The ED50 range ≤10 ug/ml.

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 68.9 kDa

Concentration: 1 mg/mL

Appearance: Liquid protein

Physical form description:

Reconstitution Instructions:

Amino acid sequence: The target is expressed with the sequence (Lys1-Arg638) of Human p!gR with a His tag at the C-terminus.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans