Recombinant Human TGFA Protein | PH0143E2

Recombinant Human TGFA Protein | PH0143E2 | Gentaur UK, US & Europe Distribution

Short Description: Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family, TGF-α is a mitogenic polypeptide. The protein becomes activated when binding to receptors capable of protein kinase activity for cellular signaling. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate.

Product Type: Cytokine

Form: lyophilized

Purity: Greater than 95% by SDS-PAGE

Storage: -70°C

Buffer: 0.2 μm filtered 50 mM Tris, 100 mM NaCl, pH 8.0