Recombinant Murine Interleukin-27/p28 (IL-30) | 4187

The p28 subunit of IL-27 (IL-27/p28), also known as Interleukin-30 (IL-30), is a member of the IL-12 family of cytokines.  When combined with EBI3 (Epstein-Barr virus induced gene 3), p28 forms a heterodimer known as IL-27.  p28 is thought to be a pro-inflammatory cytokine inducing immuno-modulatory effects, but the details of these effects are currently unclear and research is focused on delineating its specific biological functions.  Recombinant mouse p28 is a non-glycosylated protein, containing 207 amino acids, with a molecular weight of 23.7 kDa.

4187 | Recombinant Murine Interleukin-27/p28 IL-30 DataSheet

Biomolecule/Target: IL-27/p28

Synonyms: Interleukin-30, IL-30, IL-27/p28, p28, Interleukin-27, Interleukin-27/p28, IL-27, Interleukin-27 subunit , IL-27 subunit , IL27-A, Il27, Il27a, IL-27p28.

Alternates names: CCL24

Taglines: A regulator of B- and T-lymphocyte's activities

NCBI Gene ID #: 56221

NCBI Gene Symbol: CCL24

Gene Source: Murine

Accession #: Q9JKC0

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml.

Biological activity: Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 10.3 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV