Recombinant SARS-CoV-2 NSP12 | P1670

The replication of Coronavirus is operated by multiple non-structural proteins (nsps). The viral genomic RNA is translated from two open reading frames (ORFs), ORF1a and ORF1b. The encoded replicase polyproteins, pp1a and pp1ab, are further processed to produce nsps. NSP12 encoded by ORF1b has the viral RNA-dependent RNA polymerase (RdRp) motif. It is the catalytic core of the RNA replicase.

P1670 | Recombinant SARS-CoV-2 NSP12 DataSheet

Biomolecule/Target :

Synonyms: RNA-directed RNA polymerase, RdRp, RdRp catalytic domain, nsp12, SARS-CoV-2 NSP12; COVID-19 NSP12; 2019-nCoV NSP12; Non-Structural Protein 12; nsp12

Alternates names: RNA-directed RNA polymerase, RdRp, RdRp catalytic domain, nsp12, SARS-CoV-2 NSP12; COVID-19 NSP12; 2019-nCoV NSP12; Non-Structural Protein 12; nsp12

Taglines: Viral RNA-dependent RNA polymerase

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source: Coronavirus

Accession #: QHD43415.1

Recombinant: 1

Source: E.coli

Purity by SDS-PAGE: ≥ 90% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level:

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Binding Capacity:

Unit Definition:

Molecular Weight: 39.4 kDa

Concentration:

Appearance: Lyophilized protein

Physical form description:

Reconstitution Instructions: Reconstitute in sterile water to a concentration of 1 mg/ml.

Amino acid sequence: The target protein is expressed with the sequence Asp4891-Val5212 of SARS-CoV-2 NSP12 with a His tag at the C-terminus.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans