REG1A polyclonal Antibody | BS7749

REG1A polyclonal Antibody | BS7749 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: The regeneration (Reg) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV. They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Reg Iα (regenerating islet-derived I alpha), also known as Lithostathine-1α, PSPS, REG, P19 or PTP, is a 166 amino acid protein that contains one C-type lectin domain and belongs to the Reg family of secretory proteins. Expressed at high levels in pancreas and fetal brain and at lower levels in adult brain, Reg Iα is thought to inhibit spontaneous calcium carbonate precipitation and may also be associated with regeneration of brain and pancreas tissue, as well as with neuronal sprouting. The gene encoding Reg Iα is tandemly clustered with other Reg proteins on a region of human chromosome 2, suggesting that several Reg proteins may have arisen from a gene duplication event.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: REG1A polyclonal Antibody detects endogenous levels of REG1A protein.

Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine 1 beta; Lithostathine-1-alpha; P19; Pancreatic stone protein 2; Pancreatic stone protein; Pancreatic thread protein; PSP; PSPS; PSPS1; PSPS2; PTP; REG 1 beta; REG; REG-1-alpha; REG1A; REG1A_HUMAN; REG1B; Regenerating islet derived protein 1 beta; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; REGL;

Immunogen: Recombinant full length Human REG1A.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: