LBD
REG3A Antibody (N-term) [APR06151G]
- SKU:
- LBD-APR06151G
- Availability:
- Usually ships in 5 working days
Description
REG3A Antibody (N-term) [APR06151G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This REG3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human REG3A.
Cellular Localisation: Secreted. Note=Found in the apical region of pancreatic acinar cells
Molecular Weight: 19395
Clone: Polyclonal
Gene Name: REG3A
Gene ID: 5068
Function: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
Summary: Tissue Location: Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level) . Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: FC, WB
Dilution: WB--1:1000
Synonyms: Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1