REG4 polyclonal Antibody | BS60517

REG4 polyclonal Antibody | BS60517 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Reg IV is part of the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric and intestinal cell proliferation and differentiation. Reg IV is a 158-amino acid secretory protein implicated in cell regeneration and/or survival with a definite growth stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate and other types of cancer. Reg IV-positive tumor cells display different phenotypes including mucus-secreting, enterocyte-like, and undifferentiated.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: REG4 polyclonal Antibody detects endogenous levels of REG4 protein.

Molecular Weight: ~ 18 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV; REG4; GISP; RELP; ITGA5; FNRA

Immunogen: A synthetic peptide corresponding to residues in Human REG4

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Contribution of ECM and Cytoskeletal Factors to EMT,