Reparixin | B2469

Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC₅₀s of 1 and 100 nM, respectively. Blocks a range of activities including leukocyte recruitment and IL-8 signaling.

Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC₅₀s of 1 and 100 nM, respectively. Blocks a range of activities including leukocyte recruitment and IL-8 signaling.

B2469 | Reparixin DataSheet

Alternate Name/Synonyms: DF 1681Y; (R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propanamide; Repertaxin; DF-1681Y

Appearance: White solid

Formulation:

CAS Number: 266359-83-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₂₁NO₃S

Molecular Weight: 289.39

Cell-Permeable?: True

Purity: ≥98%

Solubilities: >100 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation

MDL Number:

PubChem CID: 9838712

SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)NS(=O)(=O)C

InChi: InChI=1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1

InChi Key: KQDRVXQXKZXMHP-LLVKDONJSA-N