Description
Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC₅₀s of 1 and 100 nM, respectively. Blocks a range of activities including leukocyte recruitment and IL-8 signaling.
Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC₅₀s of 1 and 100 nM, respectively. Blocks a range of activities including leukocyte recruitment and IL-8 signaling.
Alternate Name/Synonyms: DF 1681Y; (R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propanamide; Repertaxin; DF-1681Y
Appearance: White solid
Formulation:
CAS Number: 266359-83-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₂₁NO₃S
Molecular Weight: 289.39
Cell-Permeable?: True
Purity: ≥98%
Solubilities: >100 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation
MDL Number:
PubChem CID: 9838712
SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)NS(=O)(=O)C
InChi: InChI=1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1
InChi Key: KQDRVXQXKZXMHP-LLVKDONJSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |