Description
A selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in humans. Displays antitumor and antiviral properties. Stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 upregulation.
Resiquimod is a selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in humans. Displays antitumor and antiviral properties.
Alternate Name/Synonyms: 1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; R-848
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 144875-48-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₂N₄O₂
Molecular Weight: 314.38
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A Toll-like receptor 7 (TLR-7) agonist
MDL Number: MFCD00937759
PubChem CID: 159603
SMILES: CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
InChi: InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)
InChi Key: BXNMTOQRYBFHNZ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |